Anti-H2B clustered histone 18 antibodies are used for the immunodetection of the protein encoded by the H2BC18 gene. In humans, the canonical protein has a reported length of 126 amino acid residues and a mass of 13.9 kDa. Its subcellular localization is in the nucleus and chromosomes. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Histone H2B protein family, it is an important component of nucleosome. Post-translational modifications have been described, including glycosylation, ubiquitination and phosphorylation. Other names for this target antigen include histone cluster 2 H2B family member f, histone cluster 2, H2bf, and histone H2B type 2-F.