Anti-SHH signaling and ciliogenesis regulator SDCCAG8 antibodies are used for the immunodetection of the protein encoded by the SDCCAG8 gene. In humans, the canonical protein has a reported length of 713 amino acid residues and a mass of 82.7 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors. It is reported to play a role in the establishment of cell polarity and epithelial lumen formation (By similarity). The gene encoding this protein is implicated in Senior-Loken syndrome. Other names for this target antigen include CCCAP, CCCAP SLSN7, HSPC085, NPHP10, NY-CO-8, SLSN7, hCCCAP, and BBS16. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.