Anti-protein tyrosine phosphatase non-receptor type 2 antibodies are used for the immunodetection of the protein encoded by the PTPN2 gene. In humans, the canonical protein has a reported length of 415 amino acid residues and a mass of 48.5 kDa. Its subcellular localization is in the ER. Alternative splicing is reported to yield 4 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the Protein-tyrosine phosphatase protein family, it is known to be involved with the differentiation of certain cell types. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include PTPT, TC-PTP, TCELLPTP, TCPTP, tyrosine-protein phosphatase non-receptor type 2, and PTN2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.