Anti-protein tyrosine phosphatase non-receptor type 12 antibodies are used for the immunodetection of the protein encoded by the PTPN12 gene. In humans, the canonical protein has a reported length of 780 amino acid residues and a mass of 88.1 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Protein-tyrosine phosphatase protein family, it is known to be involved with protein dephosphorylation. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include PTPG1, tyrosine-protein phosphatase non-receptor type 12, protein-tyrosine phosphatase G1, and PTP-PEST. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.