Anti-MLLT10 histone lysine methyltransferase DOT1L cofactor antibodies are used for the immunodetection of the protein encoded by the MLLT10 gene. In humans, the canonical protein has a reported length of 1068 amino acid residues and a mass of 113.3 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 4 different isoforms for this protein. It is noted to be expressed abundantly in testis. It is suspected to be involved in transcriptional regulation. Other names for this target antigen include protein AF-10, ALL1-fused gene from chromosome 10 protein, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, and AF10. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.