Anti-FAM3 metabolism regulating signaling molecule D antibodies are used for the immunodetection of the protein encoded by the FAM3D gene. In humans, the canonical protein has a reported length of 224 amino acid residues and a mass of 25 kDa. It is known to be a secreted protein. It is found to be highly expressed in the placenta and weakly expressed in small intestine. It is a member of the FAM3 protein family. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include Oncoprotein-induced transcript 1, cytokine-like protein EF-7, family with sequence similarity 3 member D, and protein FAM3D. Gene orthologs have been identified in the mouse, rat, bovine, chimpanzee and chicken species.