Anti-sodium channel epithelial 1 subunit gamma antibodies are used for the immunodetection of the protein encoded by the SCNN1G gene. In humans, the canonical protein has a reported length of 649 amino acid residues and a mass of 74.3 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in the kidney. A member of the Amiloride-sensitive sodium channel (TC 1.A.6) protein family, it is known to be involved with the transport of ions. Post-translational modifications have been described, including glycosylation, ubiquitination, protein cleavage and phosphorylation. The gene encoding this protein is implicated in Liddle syndrome. Other names for this target antigen include ENaCg, ENaCgamma, LDLS2, PHA1, PHA1B3, SCNEG, amiloride-sensitive sodium channel subunit gamma, and BESC3. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.