Anti-SRY-box transcription factor 14 antibodies are used for the immunodetection of the protein encoded by the SOX14 gene. In humans, the canonical protein has a reported length of 240 amino acid residues and a mass of 26.5 kDa. Its subcellular localization is in the nucleus. It is known to act as a negative regulator of transcription. Other names for this target antigen include transcription factor SOX-14, HMG box transcription factor SOX-14, SRY (sex determining region Y)-box 14, SRY-box 14, and SOX28. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.