Anti-URB2 ribosome biogenesis homolog antibodies are used for the immunodetection of the protein encoded by the URB2 gene. In humans, the canonical protein has a reported length of 1524 amino acid residues and a mass of 170.5 kDa. Its subcellular localization is in the nucleus. It is known to be important for hematopietic stem cell development through the regulation of p53/TP53 pathway. Other names for this target antigen include NET10, NPA2, unhealthy ribosome biogenesis protein 2 homolog, URB2 ribosome biogenesis 2 homolog, nucleolar preribosomal-associated protein 1, and KIAA0133. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.