Anti-contactin associated protein 2 antibodies are used for the immunodetection of the protein encoded by the CNTNAP2 gene. In humans, the canonical protein has a reported length of 1331 amino acid residues and a mass of 148.2 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in the nervous system. A member of the Neurexin protein family, it is known to be required for gap junction formation (Probable). Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Autism. Other names for this target antigen include CASPR2, CDFE, NRXN4, PTHSL1, contactin-associated protein-like 2, and AUTS15. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.