Anti-COPI coat complex subunit zeta 1 antibodies are used for the immunodetection of the protein encoded by the COPZ1 gene. In humans, the canonical protein has a reported length of 177 amino acid residues and a mass of 20.2 kDa. Its subcellular localization is in the membrane, cytoplasmic vesicles, Golgi, and cytoplasm. Alternative splicing is reported to yield 5 different isoforms for this protein. A member of the Adaptor complexes small subunit protein family, it is known to be involved with intracellular protein transport. Other names for this target antigen include COPZ, HSPC181, zeta-COP, zeta1-COP, coatomer subunit zeta-1, and CGI-120. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.