Anti-protein tyrosine phosphatase non-receptor type 13 antibodies are used for the immunodetection of the protein encoded by the PTPN13 gene. In humans, the canonical protein has a reported length of 2485 amino acid residues and a mass of 276.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in keratinocytes. A member of the Protein-tyrosine phosphatase protein family, it is reported to be a tyrosine phosphatase, which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. Other names for this target antigen include PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E, and FAP-1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.