Anti-adenylosuccinate synthase 2 antibodies are used for the immunodetection of the protein encoded by the ADSS2 gene. In humans, the canonical protein has a reported length of 456 amino acid residues and a mass of 50.1 kDa. Its subcellular localization is in the mitochondria and cytoplasm. A member of the Adenylosuccinate synthetase protein family, it is known to play an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Other names for this target antigen include ADSS, adenylosuccinate synthetase isozyme 2, AMPSase 2, IMP--aspartate ligase 2, and ADEH. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.