Anti-DAB adaptor protein 2 antibodies are used for the immunodetection of the protein encoded by the DAB2 gene. In humans, the canonical protein has a reported length of 770 amino acid residues and a mass of 82.4 kDa. Its subcellular localization is in the cytoplasmic vesicles and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be expressed in deep invaginations, inclusion cysts and the surface epithelial cells of the ovary. It is a reported adaptor protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include DOC2, DAB2, clathrin adaptor protein, Dab, mitogen-responsive phosphoprotein, homolog 2, adaptor molecule disabled-2, and DOC-2. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.