Anti-gamma-aminobutyric acid type A receptor subunit alpha 3 antibodies are used for the immunodetection of the protein encoded by the GABRA3 gene. In humans, the canonical protein has a reported length of 492 amino acid residues and a mass of 55.2 kDa. Its subcellular localization is in the cell membrane. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, it is known to be involved with signal transduction pathways. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Epilepsy. Other names for this target antigen include gamma-aminobutyric acid receptor subunit alpha-3, GABA(A) receptor subunit alpha-3, GABA(A) receptor, alpha 3, gamma-aminobutyric acid (GABA) A receptor, alpha 3, and EPILX2. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.