Anti-peptidase, mitochondrial processing subunit alpha antibodies are used for the immunodetection of the protein encoded by the PMPCA gene. In humans, the canonical protein has a reported length of 525 amino acid residues and a mass of 58.3 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 2 different isoforms for this protein. It is widely expressed across many tissue types. It is a member of the Peptidase M16 protein family. The gene encoding this protein is implicated in Spinocerebellar ataxia. Other names for this target antigen include CLA1, CPD3, INPP5E, MAS2, P-55, SCAR2, mitochondrial-processing peptidase subunit alpha, and Alpha-MPP. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.