Anti-ADP-ribosyltransferase 3 (inactive) antibodies are used for the immunodetection of the protein encoded by the ART3 gene. In humans, the canonical protein has a reported length of 389 amino acid residues and a mass of 43.9 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to have testis-specific expression. It is a member of the Arg-specific ADP-ribosyltransferase protein family. Post-translational modifications have been described, including O-glycosylation. Other names for this target antigen include ecto-ADP-ribosyltransferase 3, ADP-ribosyltransferase C2 and C3 toxin-like 3, NAD(P)(+)--arginine ADP-ribosyltransferase 3, mono(ADP-ribosyl)transferase 3, mono-ADP-ribosyltransferase, and ARTC3. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species.