Anti-Ephrin A3 antibodies are used in the immunodetection of the protein encoded by the EFNA3 gene. In humans, the canonical protein has a reported length of 238 amino acid residues and a mass of 26.4 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. A member of the Ephrin protein family, it is known to be involved with axon guidance and cell to cell signaling. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include EPLG3, Ehk1-L, LERK3, EFL-2, EHK1 ligand, LERK-3, eph-related receptor tyrosine kinase ligand 3, and EFL2.