Anti-H2BC17 antibodies are used in the immunodetection of the protein H2B clustered histone 17. In humans, the canonical protein has a reported length of 126 amino acid residues and a mass of 13.9 kDa. Its subcellular localization is in the nucleus and chromosomes. It is notably widely expressed in many tissue types. A member of the Histone H2B protein family, H2BC17 is an important component of nucleosome. Post-translational modifications have been described, including glycosylation, ubiquitination and phosphorylation. Synonyms for this target antigen include H2B/n, H2BFN, HIST1H2BO, dJ193B12.2, histone H2B type 1-O, H2B histone family, member N, histone 1, H2bo, and H2B.2. H2BC17 gene orthologs have been reported in the mouse, rat and chimpanzee species.