Anti-ERCC1 antibodies are used in the immunodetection of the protein ERCC excision repair 1, endonuclease non-catalytic subunit. In humans, the canonical protein has a reported length of 297 amino acid residues and a mass of 32.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the ERCC1/RAD10/SWI10 protein family, ERCC1 is reported to be a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Synonyms for this target antigen include RAD10, UV20, DNA excision repair protein ERCC-1, excision repair cross-complementation group 1, and COFS4. ERCC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Over 210 citations in the literature describe the use of ERCC1 antibodies in research. Western Blot is a widely used application for these antibodies. Flow Cytometry, Immunofluorescence, and Immunohistochemistry are also common applications.