Anti-RTKN2 antibodies are used in the immunodetection of the protein rhotekin 2. In humans, the canonical protein has a reported length of 609 amino acid residues and a mass of 69.3 kDa. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in lymphocytes, CD4 positive T-cells and bone marrow-derived cells. RTKN2 is believed to play an important role in lymphopoiesis. The RTKN2 marker can be used to identify Alveolar Type I Cells and Regulatory T Cells.* Synonyms for this target antigen include PH domain-containing family K member 1 and pleckstrin homology domain-containing family K member 1. RTKN2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some Rtkn2 antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4