Anti-T-cell leukemia, homeobox 1 antibodies enable researchers to detect and measure the T-cell leukemia, homeobox 1 antigen in biological samples. This target is a reported synonym of the TLX1 gene, which encodes T cell leukemia homeobox 1. This protein is known to function in the regulation of transcription, among other biological roles. The human version of T-cell leukemia, homeobox 1 has a canonical amino acid length of 330 residues and a protein mass of 34.4 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the nucleus of cells.