Anti-sex comb on midleg homolog 1 antibodies enable researchers to detect and measure the sex comb on midleg homolog 1 antigen in biological samples. This target is a reported synonym of the SCMH1 gene, which encodes Scm polycomb group protein homolog 1. This protein is known to function in the regulation of transcription, among other biological roles. The human version of sex comb on midleg homolog 1 has a canonical amino acid length of 660 residues and a protein mass of 73.4 kilodaltons, although 6 isoforms have been identified. It is reported to be localized in the nucleus of cells. Other names for this target antigen include Scml3, polycomb protein SCMH1, and sex comb on midleg homolog 1.