Anti-GRAMD2A antibodies are used in the immunodetection of the protein GRAM domain containing 2A. In humans, the canonical protein has a reported length of 354 amino acid residues and a mass of 40.2 kDa. Its subcellular localization is in the ER and cell membrane. GRAMD2A is known to participate in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. The GRAMD2A marker can be used to identify Brain Ependymal Non-Neuronal Cells and Alveolar Type I Cells.* Synonyms for this target antigen include GRAM domain containing 2, GRAM domain-containing protein 2, and GRAM domain-containing protein 2A. GRAMD2A gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Immunofluorescence is the most common application for the GRAMD2A antibodies listed below. Western Blot, Immunocytochemistry, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4