Anti-transketolase like 2 antibodies are used for the immunodetection of the protein encoded by the TKTL2 gene. In humans, the canonical protein has a reported length of 626 amino acid residues and a mass of 67.9 kDa. It is notably expressed in hepatoma cancer cells. A member of the Transketolase protein family, it is known to play an important role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Other names for this target antigen include transketolase-like protein 2 and testis tissue sperm-binding protein Li 39a. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. Some transketolase like 2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.