Anti-C1QC antibodies are used in the immunodetection of the protein complement C1q C chain. In humans, the canonical protein has a reported length of 245 amino acid residues and a mass of 25.8 kDa. It has been described to be a secreted protein. It is notably expressed in the prostate, gallbladder, fallopian tube, endometrium, and colon. C1QC is known to be involved with immune response pathways and innate immune responses.
The C1QC marker can be used to identify Thymic Macrophages, Thymic Cortical Macrophages, and Thymic Medullary Macrophages.* Synonyms for this target antigen include C1QG, complement C1q subcomponent subunit C, complement component 1, q subcomponent, C chain, complement component 1, q subcomponent, gamma polypeptide, and C1QD3. C1QC gene orthologs have been reported in the mouse, rat, bovine, frog and chicken species. A number of C1QC antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4