Anti-MAP4K2 antibodies are used in the immunodetection of the protein mitogen-activated protein kinase kinase kinase kinase 2. In humans, the canonical protein has a reported length of 820 amino acid residues and a mass of 91.6 kDa. Its subcellular localization is in the cell membrane, Golgi, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in germinal center but not mantle zone B-cells. A member of the STE Ser/Thr protein kinase protein family, MAP4K2 is reported to be a serine/threonine-protein kinase, which acts as an essential component of the MAP kinase signal transduction pathway. Synonyms for this target antigen include GCK, RAB8IP, B lymphocyte serine/threonine protein kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, and BL44. MAP4K2 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Some MAP4K2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.