Anti-PYGM antibodies are used in the immunodetection of the protein glycogen phosphorylase, muscle associated. In humans, the canonical protein has a reported length of 842 amino acid residues and a mass of 97.1 kDa. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the skeletal muscle. A member of the Glycogen phosphorylase protein family, PYGM is reported to be an allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. Synonyms for this target antigen include glycogen phosphorylase, muscle form, myophosphorylase, phosphorylase, glycogen, muscle, and GSD5. PYGM gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. A number of PYGM antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.