Anti-BSND antibodies are used in the immunodetection of the protein barttin CLCNK type accessory subunit beta. In humans, the canonical protein has a reported length of 320 amino acid residues and a mass of 35.2 kDa. Its subcellular localization is in the cell membrane and cytoplasm. It is notably expressed in the kidney. BSND is known to function as a beta-subunit for CLCNKA and CLCNKB chloride channels. Post-translational modifications have been described, including palmitoylation. The BSND marker can be used to identify Pulmonary Ionocytes.* Synonyms for this target antigen include DFNB73, barttin, Bartter syndrome, infantile, with sensorineural deafness (Barttin), barttin CLCNK type accessory beta subunit, and BART. BSND gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4