Anti-yippee like 5 antibodies are used for the immunodetection of the protein encoded by the YPEL5 gene. In humans, the canonical protein has a reported length of 121 amino acid residues and a mass of 13.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. A member of the Yippee protein family, it is a known component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Other names for this target antigen include CGI-127 and protein yippee-like 5. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some yippee like 5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, and Immunohistochemistry are also common applications.