Anti-lysine demethylase 8 antibodies are used for the immunodetection of the protein encoded by the KDM8 gene. In humans, the canonical protein has a reported length of 416 amino acid residues and a mass of 47.3 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be weakly expressed in most cells. It is reported to be a bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase. Other names for this target antigen include JmjC arginyl-hydroxylase, L-arginine (3R)-hydroxylase KDM8, arginyl C3-hydroxylase KDM8, jmjC domain-containing protein 5, and bifunctional peptidase and arginyl-hydroxylase JMJD5. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some lysine demethylase 8 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.