Anti-catenin alpha like 1 antibodies are used for the immunodetection of the protein encoded by the CTNNAL1 gene. In humans, the canonical protein has a reported length of 734 amino acid residues and a mass of 81.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is widely expressed across many tissue types. A member of the Vinculin/alpha-catenin protein family, it is believed to modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). Other names for this target antigen include CLLP, alpha-CATU, alpha-catulin, alpha-catenin-related protein, alpha2-catulin, and ACRP. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some catenin alpha like 1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.