Anti-NAXE antibodies are used in the immunodetection of the protein NAD(P)HX epimerase. In humans, the canonical protein has a reported length of 288 amino acid residues and a mass of 31.7 kDa. Its subcellular localization is in the mitochondria and is secreted. Up to 2 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the NnrE/AIBP protein family, NAXE is known to catalyze the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. The NAXE gene has been associated with the disease, Encephalopathy. Synonyms for this target antigen include AI-BP, apoA-I binding protein, apolipoprotein A-I-binding protein, yjeF N-terminal domain-containing protein 1, yjeF_N1, and NAD(P)H-hydrate epimerase. NAXE gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some NAXE antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.