Anti-polymerase (DNA) epsilon, catalytic subunit antibodies are used in antigen-specific immunodetection in biological samples. The target polymerase (DNA) epsilon, catalytic subunit is a known alias name of the protein DNA polymerase epsilon, catalytic subunit, encoded by the POLE gene in humans. This 2286-amino acid residue protein is reported to be a catalytic component of the DNA polymerase epsilon complex. It is localized to the nucleus of the cell.