Anti-PLAG1 zinc finger antibodies are used in the immunodetection of the protein encoded by the PLAG1 gene. In humans, the canonical protein has a reported length of 500 amino acid residues and a mass of 55.9 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in fetal tissues such as lung, liver and kidney. A member of the Krueppel C2H2-type zinc-finger protein family, it is reported to be a transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Post-translational modifications have been described, including sumoylation, acetylation. Other names for this target antigen include SGPA, SRS4, ZNF912, zinc finger protein PLAG1, COL1A2/PLAG1 fusion, and PSA.