Anti-DEAH-box helicase 16 antibodies are used in the immunodetection of the protein encoded by the DHX16 gene. In humans, the canonical protein has a reported length of 1041 amino acid residues and a mass of 119.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be expressed in the spleen, thyroid and testis. A member of the DEAD box helicase protein family, it is said to be required for pre-mRNA splicing as component of the spliceosome. Other names for this target antigen include DDX16, NMOAS, PRO2014, PRP8, PRPF2, Prp2, pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16, and DBP2.