Anti-POLA2 antibodies are used in the immunodetection of the protein DNA polymerase alpha 2, accessory subunit. In humans, the canonical protein has a reported length of 598 amino acid residues and a mass of 65.9 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the DNA polymerase alpha subunit B protein family, POLA2 is reported to be an accessory subunit the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. Synonyms for this target antigen include DNA polymerase alpha 70 kDa subunit, polymerase (DNA directed), alpha 2 (70kD subunit), polymerase (DNA directed), alpha 2, accessory subunit, and DNA polymerase alpha subunit B. POLA2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of POLA2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.