Anti-shugoshin 2 antibodies are used in the immunodetection of the protein encoded by the SGO2 gene. In humans, the canonical protein has a reported length of 1265 amino acid residues and a mass of 144.7 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Shugoshin protein family, it is known to be involved with cell division. Other names for this target antigen include shugoshin-like 2.