Anti-KPNB1 antibodies are used in the immunodetection of the protein karyopherin subunit beta 1. In humans, the canonical protein has a reported length of 876 amino acid residues and a mass of 97.2 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Importin beta protein family, KPNB1 is reported to function in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Synonyms for this target antigen include IPO1, IPOB, Impnb, NTF97, importin subunit beta-1, PTAC97, importin 1, and IMB1. KPNB1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of KPNB1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.