Anti-RIBOPHORIN I antibodies are used in the immunodetection of the protein encoded by the RPN1 gene. In humans, the canonical protein has a reported length of 607 amino acid residues and a mass of 68.6 kDa. Its subcellular localization is in the ER. It is reported to be expressed in all tissues tested. A member of the OST1 protein family, it is a known subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include RBPH1, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, RPN-I, dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit, and OST1.