Anti-IGKV1-8 antibodies are used in the immunodetection of the protein immunoglobulin kappa variable 1-8. In humans, the canonical protein has a reported length of 115 amino acid residues and a mass of 12.5 kDa. Its subcellular localization is in the cell membrane and is secreted. IGKV1-8 is known to be involved with adaptive immune responses.