Anti-SCO1 antibodies are used in the immunodetection of the protein synthesis of cytochrome C oxidase 1. In humans, the canonical protein has a reported length of 301 amino acid residues and a mass of 33.8 kDa. Its subcellular localization is in the mitochondria. It is reported to be highly expressed in the tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain. It is a member of the SCO1/2 protein family. The SCO1 gene has been associated with the disease, Mitochondrial complex IV deficiency. Synonyms for this target antigen include SCOD1, protein SCO1 homolog, mitochondrial, SCO cytochrome c oxidase assembly protein 1, SCO cytochrome oxidase deficient homolog 1, SCO1, cytochrome c oxidase assembly protein, and MC4DN4. SCO1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Some SCO1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.