Anti-R-Spondin 3 Antibody Products

Anti-R-Spondin 3 antibodies are used for the immunodetection of the protein encoded by the RSPO3 gene. In humans, the canonical protein has a reported length of 272 amino acid residues and a mass of 30.9 kDa. It is known to be a secreted protein. Alternative splicing is reported to yield 2 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the R-spondin protein family, it is reported to be an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis.

The R-spondin 3 marker can be used to characterize Gray Matter MGE Interneurons, Brain Splatter Neurons, Pericryptal Fibroblastic Sheath Cells, and Type 1 Thymic Fibroblasts.* Other names for this target antigen include protein with TSP type-1 repeat, roof plate-specific spondin-3, thrombospondin type-1 domain-containing protein 2, thrombospondin, type I, domain containing 2, and R-spondin 3 homolog. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of R-Spondin 3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.