Anti-Glycine Receptor Alpha 3 antibodies are used in the immunodetection of the protein encoded by the GLRA3 gene. In humans, the canonical protein has a reported length of 464 amino acid residues and a mass of 53.8 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be widely distributed throughout the central nervous system. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, it is known to be involved with chemical synaptic transmission and protein oligomerization. Post-translational modifications have been described, including phosphorylation and glycosylation. Other names for this target antigen include glycine receptor, alpha-3 polypeptide, ligand gated ion channel, and glycine receptor subunit alpha-3.