Anti-SESN1 antibodies are used in the immunodetection of the protein sestrin 1. In humans, the canonical protein has a reported length of 492 amino acid residues and a mass of 56.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the Sestrin protein family, SESN1 is known to function as a intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. Synonyms for this target antigen include SEST1, p53 activated gene 26, p53 regulated PA26 nuclear protein, and PA26. SESN1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SESN1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.