Anti-CXADR antibodies are used in the immunodetection of the protein CXADR Ig-like cell adhesion molecule. In humans, the canonical protein has a reported length of 365 amino acid residues and a mass of 40 kDa. Its subcellular localization is in the cell membrane. Up to 7 different isoforms have been reported for this protein. It is reported to be expressed in the pancreas, brain, heart, small intestine, testis, prostate and at a lower level in the liver and lung. CXADR is a known component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Synonyms for this target antigen include CAR4/6, HCAR, coxsackievirus and adenovirus receptor, 46 kD coxsackievirus and adenovirus receptor (CAR) protein, CVB3-binding protein, and CAR. CXADR gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of CXADR antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.