Anti-DNA Helicase B antibodies are used for the immunodetection of the protein encoded by the HELB gene. In humans, the canonical protein has a reported length of 1087 amino acid residues and a mass of 123.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in the testis and thymus and weakly in the liver, spleen, kidney and brain. A member of the RecD protein family, it is known to be involved with DNA damage pathways and DNA repair. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include helicase (DNA) B. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some DNA Helicase B antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.