Anti-Coronin 7 antibodies are used in the immunodetection of the protein encoded by the CORO7 gene. In humans, the canonical protein has a reported length of 925 amino acid residues and a mass of 100.6 kDa. Its subcellular localization is in the cytoplasmic vesicles, golgi, and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is widely expressed across many tissue types. A member of the WD repeat coronin protein family, it is known to be a F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. Post-translational modifications have been described, including ubiquitination and phosphorylation. Other names for this target antigen include 70 kDa WD repeat tumor rejection antigen homolog.