The Biocompare Microscopes and Cell Imaging Systems search tool enables users to compare different instrument specifications, features, and applications to best serve the unique imaging needs of biological researchers. Contemporary microscopes are stand-alone optical devices that enable the necessary magnification needed to visualize processes at the tissue and cellular levels. Thanks to advances in optical technologies, researchers today can enjoy many choices in instruments. Microscopes and imaging systems can be categorized by their general build (such as upright, inverted, or digital systems) or primary function (stereo/zoom, electron, confocal, super-resolution, in vivo imaging, or slide scanning). Another important consideration is the imaging application, as many instrument models can offer multiple capabilities, such as phase contrast, polarization, luminescence, multi-channel fluorescence, darkfield, live cell imaging, 3D imaging, time-lapse, and more. When choosing an imaging instrument, also consider useful features such as automation compatibility, customization options, remote access, and control chambers. Use the filters on the left to simplify your search and click on the products below for more information.
TIRFM is a well-established technique for live cell imaging that makes use of total internal reflection (TIR) to produce extremely high contrast, low background images. The electromagnetic field of the light extends into the sample beyond the interface by some one to two hundred nanometers yielding a very thin section of the specimen to undergo fluorescence excitation. TIRF Microscopes are used for applications such as single cell analysis, cell membrane study, surface receptor activity, cytoskeleton dynamics and other live cell imaging needs. Look for platforms that are easily modified to accommodate a wide range of experimental requirements, intelligent laser safety that provides maximum protection, and easy to use, real-time control of hardware.