Simplified Tissue Clearing with RapiClear®: A One-Step Solution from SUNJIN LAB

June 04, 2026

BlueskyReddit
SUNY UB
Research Scientist

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Quality of Results

Ease-of-Optimization

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Company:

SUNJIN LAB

Product Name:

RapiClear®

Catalog Number:

#RC152

This product series allows me to easily prepare tissue clearing samples. Compared to organic solvent-based clearing agents, it is water-soluble, odorless, safer, and easier to handle. Even large specimens such as a whole rat brain can be readily rendered transparent.

Experimental Design and Results Summary

Application

Tissue Clearing , Immunofluorescence staining

Starting Material

Cell samples

Tips

Select products with different refractive indices according to the tissue thickness.

Results Summary

This product facilitates the acquisition of thick tissue images, proving particularly valuable for non-coplanar structures such as nerves and vessels. Furthermore, the enriched imaging data and details have stimulated numerous new insights.

DOI or PMID #

DOI: 10.1002/advs.202401039

Image Gallery

Summary

The Good

Maximize Signal-to-Noise Ratio

The Bad

None.

The Bottom Line

This is a whole mouse brain. Albumin–Alexa Fluor 555 was administered via intravenous injection, after which the animal was sacrificed and the brain was collected and fixed. The image was obtained following the protocol provided by RapiClear.

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